This is the main chapel of the Roman Major Seminary. Enshrined here is the original, albeit very small, famous and miraculous icon of Our Lady of Trust (Maria Santissima Madre della Fiducia).
The seminary building complex and chapel were built under the reign of Pope St. Pius X (with a newer chapel and dormatory built under the reign of Pope Paul VI).
Generations of seminarians have prayed daily before this altar. It's a lovely chapel with no pews and so everybody kneels in prayer. By divine providence, it was spared any postconciliar renovation and has great frescos.